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Genetic contributions to epigenetic-defined endotypes of allergic phenotypes in children

2024-10-04

Abstract excerpt

<h4>Background: </h4> Asthma is the most common chronic respiratory disease in children, but little is known about genetic contributions to its underlying endotypes. To address this gap, we studied the methylome, transcriptome, and genome from children with extensive phenotyping from birth. <h4>Methods</h4> We performed DNA methylation (DNAm) studies using the Asthma&Allergy array and RNA-sequencing in nasal mucos...

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Literature Corpus work
1c0cf5e0-21cd-5437-bf94-9ca54d62eafe
DOI
10.1101/2024.10.03.24314618
Open publication

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Genetic contributions to epigenetic-defined endotypes of allergic phenotypes in childrenDOI 10.1101/2024.10.03.24314618
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