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Article

Nasal DNA methylation at three CpG sites predicts childhood allergic disease

1 Dec 2022

Abstract excerpt

Childhood allergic diseases, including asthma, rhinitis and eczema, are prevalent conditions that share strong genetic and environmental components. Diagnosis relies on clinical history and measurements of allergen-specific IgE. We hypothesize that a multi-omics model could accurately diagnose childhood allergic disease. We show that nasal DNA methylation has the strongest predictive power to diagnose childhood...

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PMID: 36456559
DOI: 10.1038/s41467-022-35088-6

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