Article
Multiple variants in 5q31.1 are associated with systemic lupus erythematosus susceptibility and subphenotypes in the Han Chinese population.
The British journal of dermatology - 1 Sept 2017
Wen L L, Zhu Z W, Yang C, Liu L, Zuo X B, Morris D L, Dou J F, Ye L, Cheng Y Y, Guo H M, Huang H Q, Lin Y, Zhu C H, Tang L L, Chen M Y, Zhou Y, Ding Y T, Liang B, Zhou F S, Gao J P, Tang X F, Zheng X D, Wang W J, Yin X Y, Tang H Y, Sun L D, Yang S, Zhang X J, Sheng Y J, Cui Y
Abstract excerpt
BACKGROUND: A previous study provided evidence for a genetic association between PPP2CA on 5q31.1 and systemic lupus erythematosus (SLE) across multi-ancestral cohorts, but failed to find significant evidence for an association in the Han Chinese population. OBJECTIVES: To explore the association between this locus and SLE using data from our previously published genome-wide association study (GWAS). METHODS:...
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