Article
A single-nucleotide polymorphism of the STAT4 gene is associated with systemic lupus erythematosus (SLE) in female Chinese population.
Rheumatology international - 1 May 2012
Luan Haixia, Li Ping, Cao Chunwei, Li Chaohua, Hu Chaojun, Zhang Shulan, Zeng Xiaofeng, Zhang Fengchun, Zeng Changqing, Li Yongzhe
Abstract excerpt
Systemic lupus erythematosus (SLE) is a prototypic autoimmune disease with complex genetic inheritance. Genetic association of signal transducer and activator of transcription 4 (STAT4) with SLE susceptibility has been convincingly established in multiple populations including Asians, whereas studies of genetic relations between STAT4 polymorphisms and subphenotypes of SLE were rarely conducted. In this study, we...
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