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Article

Limitations and risks of meta-analyses of longevity studies.

Mechanisms of ageing and development - 1 Jul 2017

Sebastiani Paola, Bae Harold, Gurinovich Anastasia, Soerensen Mette, Puca Annibale, Perls Thomas T

Abstract excerpt

Searching for genetic determinants of human longevity has been challenged by the rarity of data sets with large numbers of individuals who have reached extreme old age, inconsistent definitions of the phenotype, and the difficulty of defining appropriate controls. Meta-analysis - a statistical method to summarize results from different studies - has become a common tool in genetic epidemiology to accrue large...

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Identifiers

PMID: 28143747
DOI: 10.1016/j.mad.2017.01.008
PMCID: PMC5533653

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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