Article
APOE Alleles and Extreme Human Longevity.
The journals of gerontology. Series A, Biological sciences and medical sciences - 1 Jan 2019
Sebastiani Paola, Gurinovich Anastasia, Nygaard Marianne, Sasaki Takashi, Sweigart Benjamin, Bae Harold, Andersen Stacy L, Villa Francesco, Atzmon Gil, Christensen Kaare, Arai Yasumichi, Barzilai Nir, Puca Annibale, Christiansen Lene, Hirose Nobuyoshi, Perls Thomas T
Abstract excerpt
We assembled a collection of 28,297 participants from seven studies of longevity and healthy aging comprising New England Centenarian, Long Life Family, Longevity Gene Population, Southern Italian Centenarian, Japanese Centenarian, the Danish Longevity, and the Health and Retirement Studies to investigate the association between the APOE alleles ε2ε3 and ε4 and extreme human longevity and age at death. By using...
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