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Article

Allelic variation and human longevity.

Science of aging knowledge environment : SAGE KE - 20 Jul 2005

Nebel Almut, Schreiber Stefan

Abstract excerpt

Human longevity is a complex phenotype with a strong genetic contribution. The search for allelic variation that impacts on longevity often involves population-based association studies of long-lived individuals (centenarians and nonagenarians) and younger controls. A major methodological problem with this approach is that the cases and controls in these experiments are often born several generations apart. The...

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PMID: 16034039
DOI: 10.1126/sageke.2005.29.pe23

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