Article
A Worldwide Map of Plasmodium falciparum K13-Propeller Polymorphisms.
The New England journal of medicine - 23 Jun 2016
Ménard Didier, Khim Nimol, Beghain Johann, Adegnika Ayola A, Shafiul-Alam Mohammad, Amodu Olukemi, Rahim-Awab Ghulam, Barnadas Céline, Berry Antoine, Boum Yap, Bustos Maria D, Cao Jun, Chen Jun-Hu, Collet Louis, Cui Liwang, Thakur Garib-Das, Dieye Alioune, Djallé Djibrine, Dorkenoo Monique A, Eboumbou-Moukoko Carole E, Espino Fe-Esperanza-Caridad J, Fandeur Thierry, Ferreira-da-Cruz Maria-Fatima, Fola Abebe A, Fuehrer Hans-Peter, Hassan Abdillahi M, Herrera Socrates, Hongvanthong Bouasy, Houzé Sandrine, Ibrahim Maman L, Jahirul-Karim Mohammad, Jiang Lubin, Kano Shigeyuki, Ali-Khan Wasif, Khanthavong Maniphone, Kremsner Peter G, Lacerda Marcus, Leang Rithea, Leelawong Mindy, Li Mei, Lin Khin, Mazarati Jean-Baptiste, Ménard Sandie, Morlais Isabelle, Muhindo-Mavoko Hypolite, Musset Lise, Na-Bangchang Kesara, Nambozi Michael, Niaré Karamoko, Noedl Harald, Ouédraogo Jean-Bosco, Pillai Dylan R, Pradines Bruno, Quang-Phuc Bui, Ramharter Michael, Randrianarivelojosia Milijaona, Sattabongkot Jetsumon, Sheikh-Omar Abdiqani, Silué Kigbafori D, Sirima Sodiomon B, Sutherland Colin, Syafruddin Din, Tahar Rachida, Tang Lin-Hua, Touré Offianan A, Tshibangu-wa-Tshibangu Patrick, Vigan-Womas Inès, Warsame Marian, Wini Lyndes, Zakeri Sedigheh, Kim Saorin, Eam Rotha, Berne Laura, Khean Chanra, Chy Sophy, Ken Malen, Loch Kaknika, Canier Lydie, Duru Valentine, Legrand Eric, Barale Jean-Christophe, Stokes Barbara, Straimer Judith, Witkowski Benoit, Fidock David A, Rogier Christophe, Ringwald Pascal, Ariey Frederic, Mercereau-Puijalon Odile
Abstract excerpt
BACKGROUND: Recent gains in reducing the global burden of malaria are threatened by the emergence of Plasmodium falciparum resistance to artemisinins. The discovery that mutations in portions of a P. falciparum gene encoding kelch (K13)-propeller domains are the major determinant of resistance has provided opportunities for monitoring such resistance on a global scale. METHODS: We analyzed the K13-propeller...
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