Article
[Advancement of phenotype transformation of cancer-associated fibroblasts: from genetic alterations to epigenetic modification].
Zhongguo fei ai za zhi = Chinese journal of lung cancer - 1 Feb 2015
Chen Dali, Che Guowei
Abstract excerpt
In the field of human cancer research, even though the vast majority attentions were paid to tumor cells as "the seeds", the roles of tumor microenvironments as "the soil" are gradually explored in recent years. As a dominant compartment of tumor microenvironments, cancer-associated fibroblasts (CAFs) were discovered to correlated with tumorigenesis, tumor progression and prognosis. And the exploration of the...
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