Article
Regulators of Lysosome Function and Dynamics in Caenorhabditis elegans.
G3 (Bethesda, Md.) - 10 Mar 2017
Gee Kevin, Zamora Danniel, Horm Teresa, George Laeth, Upchurch Cameron, Randall Justin, Weaver Colby, Sanford Caitlin, Miller Austin, Hernandez Sebastian, Dang Hope, Fares Hanna
Abstract excerpt
Lysosomes, the major membrane-bound degradative organelles, have a multitude of functions in eukaryotic cells. Lysosomes are the terminal compartments in the endocytic pathway, though they display highly dynamic behaviors, fusing with each other and with late endosomes in the endocytic pathway, and with the plasma membrane during regulated exocytosis and for wound repair. After fusing with late endosomes,...
Topics
- Animals
- Caenorhabditis elegans
- Cell Compartmentation
- Cell Membrane
- Cloning, Molecular
- Endocytosis
- Genes, Helminth
- Green Fluorescent Proteins
- Lysosomes
- Mutation
- Sequence Homology, Nucleic Acid