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Conserved components of the macroautophagy machinery in Caenorhabditis elegans

1 Apr 2025

Abstract excerpt

Macroautophagy involves the sequestration of cytoplasmic contents in a double-membrane autophagosome and its subsequent delivery to lysosomes for degradation and recycling. In Caenorhabditis elegans, autophagy participates in diverse processes such as stress resistance, cell fate specification, tissue remodeling, aging, and adaptive immunity. Genetic screens in C. elegans have identified a set of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40180610
DOI: 10.1093/genetics/iyaf007

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