Article
The arf-like GTPase Arl8 mediates delivery of endocytosed macromolecules to lysosomes in Caenorhabditis elegans.
Molecular biology of the cell - 15 Jul 2010
Nakae Isei, Fujino Tomoko, Kobayashi Tetsuo, Sasaki Ayaka, Kikko Yorifumi, Fukuyama Masamitsu, Gengyo-Ando Keiko, Mitani Shohei, Kontani Kenji, Katada Toshiaki
Abstract excerpt
Late endocytic organelles including lysosomes are highly dynamic acidic organelles. Late endosomes and lysosomes directly fuse for content mixing to form hybrid organelles, from which lysosomes are reformed. It is not fully understood how these processes are regulated and maintained. Here we show...
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