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Article

Matrix metalloproteinase-14 triggers an anti-inflammatory proteolytic cascade in endotoxemia.

Journal of molecular medicine (Berlin, Germany) - 1 May 2017

Aguirre Alina, Blázquez-Prieto Jorge, Amado-Rodriguez Laura, López-Alonso Inés, Batalla-Solís Estefanía, González-López Adrián, Sánchez-Pérez Moisés, Mayoral-Garcia Carlos, Gutiérrez-Fernández Ana, Albaiceta Guillermo M

Abstract excerpt

ᅟ: Matrix metalloproteinases can modulate the inflammatory response through processing of cyto- and chemokines. Among them, MMP-14 is a non-dispensable collagenase responsible for the activation of other enzymes, triggering a proteolytic cascade. To identify the role of MMP-14 during the pro-inflammatory response, wildtype and Mmp14 -/- mice were challenged with lipopolysaccharide. MMP-14 levels decreased after...

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PMID: 28120021
DOI: 10.1007/s00109-017-1510-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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