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Article

Modulation on brain gray matter activity and white matter integrity by APOE ε4 risk gene in cognitively intact elderly: A multimodal neuroimaging study.

Behavioural brain research - 30 Mar 2017

Cai Suping, Jiang Yuanyuan, Wang Yubo, Wu Xiaoming, Ren Junchan, Lee Min Seob, Lee Sunghoon, Huang Liyu

Abstract excerpt

Apolipoprotein E (APOE) ε4 allele is the genetic risk factor with the most established evidence for sporadic Alzheimer's disease. Previous neuroimaging studies have demonstrated insufficiently consistent functional and structural changes among healthy APOE ε4 carriers when compared to non-carriers. Here, in a cognitively intact elderly group (a total of 110: 45 APOE ε4 carriers, 65 non-carriers), we aimed to...

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Source

Identifiers

PMID: 28108320
DOI: 10.1016/j.bbr.2017.01.027

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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