Article
Influence of the APOE ε4 allele and mild cognitive impairment diagnosis in the disruption of the MEG resting state functional connectivity in sources space.
Journal of Alzheimer's disease : JAD - 1 Jan 2015
Cuesta Pablo, Garcés Pilar, Castellanos Nazareth P, López Maria Eugenia, Aurtenetxe Sara, Bajo Ricardo, Pineda-Pardo José Angel, Bruña Ricardo, Marín Antonio García, Delgado Marisa, Barabash Ana, Ancín Inés, Cabranes Jose Antonio, Fernandez Alberto, Del Pozo Francisco, Sancho Miguel, Marcos Alberto, Nakamura Akinori, Maestú Fernando
Abstract excerpt
The apolipoprotein E (APOE) ε4 allele constitutes the major genetic risk for the development of late onset Alzheimer's disease (AD). However, its influence on the neurodegeneration that occurs in early AD remains unresolved. In this study, the resting state magnetoencephalography(MEG) recordings were obtained from 27 aged healthy controls and 36 mild cognitive impairment (MCI) patients. All participants were...
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