Article
Genome-wide association studies provide new insights into the genetic basis of testicular germ-cell tumour.
International journal of andrology - 1 Aug 2011
Turnbull C, Rahman N
Abstract excerpt
Testicular germ-cell tumour (TGCT) is the most common cancer in young men, and genetic epidemiological studies suggest that the disease has a strong genetic basis. Until 2009, very little of this genetic component had been explained. Genome-wide association studies have since identified eight SNPs at six loci which together account for approximately 15% of the genetic risk of TGCT and offer novel biological...
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