Article
Rare de novo germline copy-number variation in testicular cancer.
American journal of human genetics - 10 Aug 2012
Stadler Zsofia K, Esposito Diane, Shah Sohela, Vijai Joseph, Yamrom Boris, Levy Dan, Lee Yoon-Ha, Kendall Jude, Leotta Anthony, Ronemus Michael, Hansen Nichole, Sarrel Kara, Rau-Murthy Rohini, Schrader Kasmintan, Kauff Noah, Klein Robert J, Lipkin Steven M, Murali Rajmohan, Robson Mark, Sheinfeld Joel, Feldman Darren, Bosl George, Norton Larry, Wigler Michael, Offit Kenneth
Abstract excerpt
Although heritable factors are an important determinant of risk of early-onset cancer, the majority of these malignancies appear to occur sporadically without identifiable risk factors. Germline de novo copy-number variations (CNVs) have been observed in sporadic neurocognitive and cardiovascular...
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