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Article

Novel Genomic Aberrations in Testicular Germ Cell Tumors by Array‐CGH, and Associated Gene Expression Changes

1 Jan 2006

Abstract excerpt

INTRODUCTION: Testicular germ cell tumors of adolescent and young adult men (TGCTs) generally have near triploid and complex karyotypes. The actual genes driving the tumorigenesis remain essentially to be identified. MATERIALS AND METHODS: To determine the detailed DNA copy number changes, and investigate their impact on gene expression levels, we performed an integrated microarray profiling of TGCT genomes and...

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PMID: 17167184
DOI: 10.1155/2006/219786

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