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Genomics implicates adaptive and innate immunity in Alzheimer's and Parkinson's diseases

4 Nov 2016

Abstract excerpt

OBJECTIVES: We assessed the current genetic evidence for the involvement of various cell types and tissue types in the etiology of neurodegenerative diseases, especially in relation to the neuroinflammatory hypothesis of neurodegenerative diseases. METHODS: We obtained large-scale genome-wide association study (GWAS) summary statistics from Parkinson's disease (PD), Alzheimer's disease (AD), and amyotrophic...

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PMID: 28097204
DOI: 10.1002/acn3.369

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