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Article

Alzheimer's Disease Variants with the Genome-Wide Significance are Significantly Enriched in Immune Pathways and Active in Immune Cells.

Molecular neurobiology - 1 Jan 2017

Jiang Qinghua, Jin Shuilin, Jiang Yongshuai, Liao Mingzhi, Feng Rennan, Zhang Liangcai, Liu Guiyou, Hao Junwei

Abstract excerpt

The existing large-scale genome-wide association studies (GWAS) datasets provide strong support for investigating the mechanisms of Alzheimer's disease (AD) by applying multiple methods of pathway analysis. Previous studies using selected single nucleotide polymorphisms (SNPs) with several thresholds of nominal significance for pathway analysis determined that the threshold chosen for SNPs can reflect the disease...

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PMID: 26746668
DOI: 10.1007/s12035-015-9670-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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