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Article

The Abl pathway bifurcates to balance Enabled and Rac signaling in axon patterning in Drosophila.

Development (Cambridge, England) - 1 Feb 2017

Kannan Ramakrishnan, Song Jeong-Kuen, Karpova Tatiana, Clarke Akanni, Shivalkar Madhuri, Wang Benjamin, Kotlyanskaya Lyudmila, Kuzina Irina, Gu Qun, Giniger Edward

Abstract excerpt

The Abl tyrosine kinase signaling network controls cell migration, epithelial organization, axon patterning and other aspects of development. Although individual components are known, the relationships among them remain unresolved. We now use FRET measurements of pathway activity, analysis of protein localization and genetic epistasis to dissect the structure of this network in Drosophila We find that the adaptor...

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Identifiers

PMID: 28087633
DOI: 10.1242/dev.143776
PMCID: PMC5341800

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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