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Article

Molecular separation of two signaling pathways for the receptor, Notch.

Developmental biology - 15 Jan 2008

Le Gall Maude, De Mattei Cordell, Giniger Edward

Abstract excerpt

Notch is required for many aspects of cell fate specification and morphogenesis during development, including neurogenesis and axon guidance. We here provide genetic and biochemical evidence that Notch directs axon growth and guidance in Drosophila via a "non-canonical", i.e. non-Su(H)-mediated, signaling pathway, characterized by association with the adaptor protein, Disabled, and Trio, an accessory factor of...

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Identifiers

PMID: 18062953
DOI: 10.1016/j.ydbio.2007.10.030
PMCID: PMC2262048

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Molecular separation of two signaling pathways for the receptor, Notch.PMID 18062953Read ↗

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