Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Exploring the roles of diaphanous and enabled activity in shaping the balance between filopodia and lamellipodia.

Molecular biology of the cell - 1 Dec 2009

Homem Catarina C F, Peifer Mark

Abstract excerpt

During migration cell protrusions power cell extension and sample the environment. Different cells produce different protrusions, from keratocytes dominated by lamellipodia, to growth cones combining filopodia and lamellipodia, to dendritic spines. One key challenge is to determine how the toolkit of actin regulators are coordinated to generate these diverse protrusive arrays. Here we use Drosophila leading-edge...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Adhesion Molecules
Share to Cytoplasm
Share to Formins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunoprecipitation

Share to Microfilament Proteins

Share to Morphogenesis

Share to Pseudopodia

Share to rho GTP-Binding Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 19846663
DOI: 10.1091/mbc.e09-02-0144
PMCID: PMC2793291

Genes

VASP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Exploring the roles of diaphanous and enabled activity in shaping the balance between filopodia and lamellipodia.PMID 19846663Read ↗

Formin’ cellular structuresSemantic proximity Read ↗

Apical targeting of the formin Diaphanous in Drosophila tubular epitheliaSemantic proximity Read ↗

Diaphanous regulates myosin and adherens junctions to control cell contractility and protrusive behavior during morphogenesis.Semantic proximity Read ↗

The Abl pathway bifurcates to balance Enabled and Rac signaling in axon patterning in Drosophila.Semantic proximity Read ↗

Apical secretion in epithelial tubes of the Drosophila embryo is directed by the Formin-family protein Diaphanous.Semantic proximity Read ↗

Twinstar, the Drosophila homolog of cofilin/ADF, is required for planar cell polarity patterning.Semantic proximity Read ↗

A contractile actomyosin network linked to adherens junctions by Canoe/afadin helps drive convergent extension.Semantic proximity Read ↗

Multicellular rosette formation links planar cell polarity to tissue morphogenesis.Semantic proximity Read ↗

Dissecting regulatory networks of filopodia formation in a Drosophila growth cone model.Semantic proximity Read ↗

Drosophila Dachsous and Fat polarize actin-based protrusions over a restricted domain of the embryonic denticle field.Semantic proximity Read ↗

Planar polarization of the denticle field in the Drosophila embryo: roles for Myosin II (zipper) and fringe.Semantic proximity Read ↗

RhoGEF2 and the formin Dia control the formation of the furrow canal by directed actin assembly during Drosophila cellularisation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.