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Article

Control of dendritic morphogenesis by Trio in Drosophila melanogaster.

PloS one - 1 Jan 2012

Shivalkar Madhuri, Giniger Edward

Abstract excerpt

Abl tyrosine kinase and its effectors among the Rho family of GTPases each act to control dendritic morphogenesis in Drosophila. It has not been established, however, which of the many GTPase regulators in the cell link these signaling molecules in the dendrite. In axons, the bifunctional guanine exchange factor, Trio, is an essential link between the Abl tyrosine kinase signaling pathway and Rho GTPases,...

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Identifiers

PMID: 22438988
DOI: 10.1371/journal.pone.0033737
PMCID: PMC3305316

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Control of dendritic morphogenesis by Trio in Drosophila melanogaster.PMID 22438988Read ↗

Dosage-sensitive, reciprocal genetic interactions between the Abl tyrosine kinase and the putative GEF trio reveal trio's role in axon pathfinding.Semantic proximity Read ↗

Rac function and regulation during Drosophila development.Semantic proximity Read ↗

The Rho guanine nucleotide exchange factor Trio is required for neural crest cell migration and interacts with Dishevelled.Semantic proximity Read ↗

The Abl pathway bifurcates to balance Enabled and Rac signaling in axon patterning in Drosophila.Semantic proximity Read ↗

The Human Rho-GEF trio and its target GTPase RhoG are involved in the NGF pathway, leading to neurite outgrowth.Semantic proximity Read ↗

Skeletal muscle deformity and neuronal disorder in Trio exchange factor-deficient mouse embryos.Semantic proximity Read ↗

The function of Drosophila larval class IV dendritic arborization sensory neurons in the larval-pupal transition is separable from their function in mechanical nociception responses.Semantic proximity Read ↗

An allele of sequoia dominantly enhances a trio mutant phenotype to influence Drosophila larval behavior.Semantic proximity Read ↗

The Abelson tyrosine kinase, the Trio GEF and Enabled interact with the Netrin receptor Frazzled in Drosophila.Semantic proximity Read ↗

Golden goal controls dendrite elongation and branching of multidendritic arborization neurons in Drosophila.Semantic proximity Read ↗

The trio guanine nucleotide exchange factor is a RhoA target. Binding of RhoA to the trio immunoglobulin-like domain.Semantic proximity Read ↗

Robo and Frazzled/DCC mediate dendritic guidance at the CNS midline.Semantic proximity Read ↗

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