Article
Regulation of mitochondrial dynamics by DISC1, a putative risk factor for major mental illness.
Schizophrenia research - 1 Sept 2017
Murphy Laura C, Millar J Kirsty
Abstract excerpt
Mitochondria are dynamic organelles that are essential to power the process of neurotransmission. Neurons must therefore ensure that mitochondria maintain their functional integrity and are efficiently transported along the full extent of the axons and dendrites, from soma to synapses. Mitochondrial dynamics (trafficking, fission and fusion) co-ordinately regulate mitochondrial quality control and function. DISC1...
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