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Article

PlA2 Polymorphism in Glycoprotein IIb/IIIa Modulates the Morphology and Nanomechanics of Platelets.

Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis - 1 Nov 2017

Todinova Svetla, Komsa-Penkova Regina, Krumova Sashka, Taneva Stefka G, Golemanov Georgy, Georgieva Galia, Tonchev Pencho, Tsankov Boris, Beshev Lyubomir, Balashev Konstantin, Andreeva Tonya D

Abstract excerpt

Glycoprotein IIb/IIIa (GPIIb/IIIa) is the most abundant platelet surface receptor for fibrinogen and von Willebrand factor. Polymorphism PlA1/A2 in the gene of GPIIb/IIIa is among the risk factors for the development of arterial and venous thrombosis. The aim of this study is to evaluate the effect of the carriage of PlA1/A2 on the size, topographic features, and membrane stiffness of platelets from healthy...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28081621
DOI: 10.1177/1076029616687847

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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