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Article

Increased platelet-collagen interaction associated with double homozygosity for receptor polymorphisms of platelet GPIa and GPIIIa.

Arteriosclerosis, thrombosis, and vascular biology - 1 Dec 2002

Pontiggia Luca, Lassila Riitta, Pederiva Stephanie, Schmid Hans-Rudolf, Burger Mirjam, Beer Juerg H

Abstract excerpt

OBJECTIVE: There is considerable controversy regarding the clinical role of the single-nucleotide polymorphisms (SNPs) of the platelet glycoprotein receptor GPIa C807T and the Pl(A1/A2) of GPIIIa as cardiovascular risk factors. We hypothesized that two combined SNPs in their homozygous prothrombotic forms could clarify their pathophysiological impact. METHODS AND RESULTS: We identified a family with a striking...

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Source

Identifiers

PMID: 12482840
DOI: 10.1161/01.atv.0000042230.26207.d2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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