Article
Atomic force microscopy-based molecular recognition of a fibrinogen receptor on human erythrocytes.
ACS nano - 24 Aug 2010
Carvalho Filomena A, Connell Simon, Miltenberger-Miltenyi Gabriel, Pereira Sónia Vale, Tavares Alice, Ariëns Robert A S, Santos Nuno C
Abstract excerpt
The established hypothesis for the increase on erythrocyte aggregation associated with a higher incidence of cardiovascular pathologies is based on an increase on plasma adhesion proteins concentration, particularly fibrinogen. Fibrinogen-induced erythrocyte aggregation has been considered to be caused by its nonspecific binding to erythrocyte membranes. In contrast, platelets are known to have a fibrinogen...
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