Article

Morphometric analysis of spread platelets identifies integrin α <sub>IIb</sub> β <sub>3</sub> -specific contractile phenotype

2018-02-13

Abstract excerpt

Haemostatic platelet function is intimately linked to cellular mechanics and cytoskeletal morphology. How cytoskeletal reorganizations give rise to a highly contractile phenotype that is necessary for clot contraction remains poorly understood. To elucidate this process in vitro , we developed a morphometric screen to quantify the spatial organization of actin fibres and vinculin adhesion sites in single spread p...

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Literature Corpus work: d453da7f-7284-59dc-81f0-5785bc799ad6
DOI: 10.1101/264804

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