Article

Function, Proteomic and miRomic Study of a Dry Immersion Model of Microgravity implicates the Wnt/Dkk1/AXIN1 axis in Prothrombotic Platelet Phenotype

2021-07-13

Abstract excerpt

<h4>Objective: </h4> Ground based research modalities of microgravity have been proposed as innovative methods to investigate the aetiology of chronic age-related conditions such as cardiovascular disease. Dry Immersion (DI), has been effectively used to interrogate the sequelae of physical inactivity (PI) and microgravity on multiple physiological systems. Herein we look at the causa et effectus of 3-day DI on pl...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: c97a009c-1ec5-5912-9625-1da35b60695f
DOI: 10.21203/rs.3.rs-610421/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Function, Proteomic and miRomic Study of a Dry Immersion Model of Microgravity implicates the Wnt/Dkk1/AXIN1 axis in Prothrombotic Platelet PhenotypeDOI 10.21203/rs.3.rs-610421/v1Read

Platelet Proteomes, Pathways, and Phenotypes as Informants of Vascular Wellness and Disease.Semantic proximity Read

Platelet Subtypes in Inflammatory SettingsSemantic proximity Read

Common anti-platelet therapies modulate procoagulant phospholipids in arterial diseaseSemantic proximity Read

Identification of a Distinct Platelet Phenotype in the Elderly: ADP Hypersensitivity Coexists With Platelet PAR (Protease-Activated Receptor)-1 and PAR-4-Mediated Thrombin Resistance.Semantic proximity Read

Notch signaling functions in non-canonical juxtacrine manner in platelets to amplify thrombogenicitySemantic proximity Read

What can the plasma proteome tell us about platelets and (vice versa)?Semantic proximity Read

Novel Approaches to Fine-Tune Therapeutic Targeting of Platelets in Atherosclerosis: A Critical Appraisal.Semantic proximity Read

Thromboelastometry and Platelet Function during Acclimatization to High AltitudeSemantic proximity Read

Hypoxia and Ischemia Promote a Maladaptive Platelet Phenotype.Semantic proximity Read

Comparison of the central human and mouse platelet signaling cascade by systems biological analysisSemantic proximity Read

Distinct Platelet Phenotype and Reactivity in Individuals with Permanent Atrial Fibrillation Treated with Direct Oral Anticoagulants: A Pilot Study.Semantic proximity Read

<i>Ex vivo</i> anticoagulants affect human blood platelet biomechanics with implications for high-throughput functional mechanophenotypingSemantic proximity Read