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Article

A pharmacogenetics-based warfarin maintenance dosing algorithm from Northern Chinese patients.

PloS one - 1 Jan 2014

Chen Jinxing, Shao Liying, Gong Ling, Luo Fang, Wang Jin'e, Shi Yi, Tan Yu, Chen Qianlong, Zhang Yu, Hui Rutai, Wang Yibo

Abstract excerpt

Inconsistent associations with warfarin dose were observed in genetic variants except VKORC1 haplotype and CYP2C9*3 in Chinese people, and few studies on warfarin dose algorithm was performed in a large Chinese Han population lived in Northern China. Of 787 consenting patients with heart-valve replacements who were receiving long-term warfarin maintenance therapy, 20 related Single nucleotide polymorphisms were...

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Source

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Identifiers

PMID: 25126975
DOI: 10.1371/journal.pone.0105250
PMCID: PMC4134280

Genes

VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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