Article
Association of apolipoprotein E (APOE) polymorphisms with warfarin maintenance dose in a northern Han Chinese population.
Lipids in health and disease - 24 Feb 2016
Liu Rui, Zhang Kui, Gong Zhi-zhong, Shi Xin-miao, Zhang Qian, Pan Xiao-dong, Dong Ran
Abstract excerpt
BACKGROUND: Apolipoprotein E (apoE) induces the uptake of vitamin K-rich lipoproteins by the liver, which likely affects inter-individual variation of warfarin dosing requirements. Associations between APOE polymorphisms and warfarin dosing were previously reported inconsistently among different ethnic groups, so the present study investigated this association in northern Han Chinese patients with mechanical...
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