Article
Development and comparison of a new personalized warfarin stable dose prediction algorithm in Chinese patients undergoing heart valve replacement.
Die Pharmazie - 1 Nov 2012
Tan S L, Li Z, Song G B, Liu L M, Zhang W, Peng J, Zhang T, Jia F F, Zhou G, Zhou H H, Zhou X M
Abstract excerpt
BACKGROUND: Pharmacogenetics-based algorithms would be especially desirable for patients undergoing heart valve replacement (HVR), who are particularly sensitive to warfarin during the initial treatment phase following surgery. We aimed to derive a warfarin dosing algorithm from data of Chinese patients undergoing HVR, and to compare it with previously published dosing algorithms as applied to our HVR patients....
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