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Article

Validation of VKORC1 and CYP2C9 genotypes on interindividual warfarin maintenance dose: a prospective study in Chinese patients.

Pharmacogenetics and genomics - 1 Mar 2009

Huang Sheng-Wen, Chen Hai-Sheng, Wang Xian-Qun, Huang Ling, Xu Ding-Li, Hu Xiao-Jia, Huang Zhi-Hui, He Yong, Chen Kai-Ming, Xiang Dao-Kang, Zou Xiao-Ming, Li Qiang, Ma Li-Qin, Wang Hao-Fei, Chen Bao-Lin, Li Liang, Jia Yan-Kai, Xu Xiang-Min

Abstract excerpt

OBJECTIVES: To develop a warfarin-dosing algorithm that could be combined with pharmacogenomic and demographic factors, and to evaluate its effectiveness in a randomized prospective controlled clinical trial. METHODS: A pharmacogenetics-based dosing model was derived using retrospective data from 266 Chinese patients and multiple linear regression analysis. To prospectively validate this model, 156 patients with...

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Source

Identifiers

PMID: 19177029
DOI: 10.1097/FPC.0b013e328326e0c7

Genes

VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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