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Article

Establishment of a Han Chinese-specific pharmacogenetic-guided warfarin dosing algorithm.

Medicine - 1 Sept 2018

Pei Lin, Tian Xiaoyi, Long Yan, Nan Wenhui, Jia Mei, Qiao Rui, Zhang Jie

Abstract excerpt

Warfarin is the most common oral anticoagulant. Because of a narrow therapeutic range, interindividual differences in drug responses, and the risk of bleeding, there are many challenges in using warfarin. We need to predict the warfarin maintenance dose. However, ethnic-specific algorithms may be required, and some Chinese algorithms do not perform adequately. Therefore, we aimed to establish a Han Chinese...

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Identifiers

PMID: 30200121
DOI: 10.1097/MD.0000000000012178
PMCID: PMC6133597

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