Article
Exploring the predictive power of polygenic scores derived from genome-wide association studies: a study of 10 complex traits.
Bioinformatics (Oxford, England) - 15 Mar 2017
So Hon-Cheong, Sham Pak C
Abstract excerpt
Motivation: It is hoped that advances in our knowledge in disease genomics will contribute to personalized medicine such as individualized preventive strategies or early diagnoses of diseases. With the growth of genome-wide association studies (GWAS) in the past decade, how far have we reached this goal? In this study we explored the predictive ability of polygenic risk scores (PRSs) derived from GWAS for a range...
Topics
Join the communities discussing this publication.