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Article

A Common Variant in the MC1R Gene (p.V92M) is associated with Alzheimer's Disease Risk.

Journal of Alzheimer's disease : JAD - 1 Jan 2017

Tell-Marti Gemma, Puig-Butille Joan Anton, Potrony Miriam, Plana Estel, Badenas Celia, Antonell Anna, Sanchez-Valle Raquel, Molinuevo José L, Lleó Alberto, Alcolea Daniel, Fortea Juan, Fernández-Santiago Rubén, Clarimón Jordi, Lladó Albert, Puig Susana

Abstract excerpt

Despite the recent identification of some novel risk genes for Alzheimer's disease (AD), the genetic etiology of late-onset Alzheimer's disease (LOAD) remains largely unknown. The inclusion of these novel risk genes to the risk attributable to the APOE gene accounts for roughly half of the total genetic variance in LOAD. The evidence indicates that undiscovered genetic factors may contribute to AD susceptibility....

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Age of Onset
Aged
Alzheimer Disease
Apolipoprotein E4
Biomarkers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Case-Control Studies

Genetic Association Studies

Receptor, Melanocortin, Type 1

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Identifiers

PMID: 28059796
DOI: 10.3233/JAD-161113

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APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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