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Article

Missense variants in CR1 are associated with increased risk of Alzheimer' disease in Han Chinese.

Neurobiology of aging - 1 Feb 2014

Ma Xiao-Ying, Yu Jin-Tai, Tan Meng-Shan, Sun Fu-Rong, Miao Dan, Tan Lan

Abstract excerpt

Complement receptor 1 (CR1) has been considered to play an important role in late-onset Alzheimer's disease (LOAD) pathogenesis. To explore the correlation between the CR1 gene and LOAD, a 2-step design study was conducted in our Northern Han Chinese population. We first sequenced the promoter, exons, the 5' and 3' untranslated regions and exon-intron boundaries of CR1 in a small sample (n = 100). This allowed us...

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Source

Identifiers

PMID: 24018213
DOI: 10.1016/j.neurobiolaging.2013.08.009

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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