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SORL1 Polymorphisms in Mexican Patients with Alzheimer's Disease.

Genes - 25 Mar 2022

Toral-Rios Danira, Ruiz-Sánchez Elizabeth, Rodríguez Nancy Lucero Martínez, Maury-Rosillo Marlene, Rosas-Carrasco Óscar, Becerril-Pérez Fernando, Mena-Barranco Francisco, Carvajal-García Rosa, Silva-Adaya Daniela, Delgado-Namorado Yair, Ramos-Palacios Gerardo, Sánchez-Torres Carmen, Campos-Peña Victoria

Abstract excerpt

The present study evaluated the risk effect of 12 Single Nucleotide Polymorphisms in the SORL1 gene in the Mexican population using Late-Onset Alzheimer's Disease (LOAD) and control subjects. Considering APOE as the strongest genetic risk factor for LOAD, we conducted interaction analyses between single nucleotide polymorphisms (SNPs) and the APOE genotype. METHODS: Patients were interviewed during their...

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Identifiers

PMID: 35456392
DOI: 10.3390/genes13040587
PMCID: PMC9026506

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