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Article

Memory Resilience to Alzheimer’s Genetic Risk: Sex Effects in Predictor Profiles

29 Nov 2016

Abstract excerpt

OBJECTIVES: Apolipoprotein E (APOE) ɛ4 and Clusterin (CLU) C alleles are risk factors for Alzheimer's disease (AD) and episodic memory (EM) decline. Memory resilience occurs when genetically at-risk adults perform at high and sustained levels. We investigated whether (a) memory resilience to AD genetic risk is predicted by biological and other risk markers and (b) the prediction profiles vary by sex and AD risk...

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PMID: 28025282
DOI: 10.1093/geronb/gbw161

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