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Article

Translational approaches to understanding resilience to Alzheimer’s disease

17 Mar 2022

Abstract excerpt

Individuals who maintain cognitive function despite high levels of Alzheimer's disease (AD)-associated pathology are said to be 'resilient' to AD. Identifying mechanisms underlying resilience represents an exciting therapeutic opportunity. Human studies have identified a number of molecular and genetic factors associated with resilience, but the complexity of these cohorts prohibits a complete understanding of...

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PMID: 35307206
DOI: 10.1016/j.tins.2022.02.005

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