Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterizing the Resilience Effect of Neurodegeneration for the Mechanistic Pathway of Alzheimer's Disease.

Journal of Alzheimer's disease : JAD - 1 Jan 2021

Hu Di, Liu Chuning, Xia Kai, Abramowitz Amy, Wu Guorong

Abstract excerpt

BACKGROUND: With the rapid development of neurobiology and neuroimaging technologies, mounting evidence shows that Alzheimer's disease (AD) is caused by the build-up of two abnormal proteins, amyloid-β plaques (A) and neurofibrillary tangles (T). Over time, these AD-related neuropathological burdens begin to spread throughout the brain, which results in the characteristic progression of symptoms in AD. OBJECTIVE:...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer Disease
Share to Brain-Derived Neurotrophic Factor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Educational Status

Share to Longitudinal Studies

Share to Models, Statistical

Share to Neurofibrillary Tangles

Share to Neuroimaging

Share to Plaque, Amyloid

Source

Identifiers

PMID: 34657890
DOI: 10.3233/JAD-215160

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterizing the Resilience Effect of Neurodegeneration for the Mechanistic Pathway of Alzheimer's Disease.PMID 34657890Read ↗

Genetic variants and functional pathways associated with resilience to Alzheimer's disease.Semantic proximity Read ↗

Genetic Variants and Functional Pathways Associated with Resilience to Alzheimer’s DiseaseSemantic proximity Read ↗

Sex differences in the genetic architecture of cognitive resilience to Alzheimer's disease.Semantic proximity Read ↗

A novel approach to resilience and its links with education and Alzheimer's disease genetics.Semantic proximity Read ↗

Translational approaches to understanding resilience to Alzheimer’s diseaseSemantic proximity Read ↗

Molecular hallmarks of excitatory and inhibitory neuronal resilience and resistance to Alzheimer’s diseaseSemantic proximity Read ↗

Memory Resilience to Alzheimer’s Genetic Risk: Sex Effects in Predictor ProfilesSemantic proximity Read ↗

Genetic architecture of resilience of executive functioning.Semantic proximity Read ↗

Candidate Molecular Subtypes of Cognitive Resilience in Alzheimer’s Disease: A Multi-Cohort Machine Learning and Neuroimaging StudySemantic proximity Read ↗

A Novel Method to Disentangle Tightly Linked Risk and Resilience Genes for Brain Disorders: Application to Alzheimer’s DiseaseSemantic proximity Read ↗

MicroRNA correlates of resilience to Alzheimer’s disease identify candidate therapeutic targets for neuroprotectionSemantic proximity Read ↗

Hippocampus Glutathione S Reductase Potentially Confers Genetic Resilience to Cognitive Decline in the AD-BXD Mouse PopulationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.