Article
Asymmetric Arginine Dimethylation Modulates Mitochondrial Energy Metabolism and Homeostasis in Caenorhabditis elegans.
Molecular and cellular biology - 15 Mar 2017
Sha Liang, Daitoku Hiroaki, Araoi Sho, Kaneko Yuta, Takahashi Yuta, Kako Koichiro, Fukamizu Akiyoshi
Abstract excerpt
Protein arginine methyltransferase 1 (PRMT-1) catalyzes asymmetric arginine dimethylation on cellular proteins and modulates various aspects of biological processes, such as signal transduction, DNA repair, and transcriptional regulation. We have previously reported that the null mutant of prmt-1 in Caenorhabditis elegans exhibits a slightly shortened life span, but the physiological significance of PRMT-1...
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