Article
The protein L-isoaspartyl-O-methyltransferase functions in the Caenorhabditis elegans stress response.
Mechanisms of ageing and development - 1 Dec 2008
Gomez Tara A, Banfield Kelley L, Clarke Steven G
Abstract excerpt
The efficient use of nutrients is important in development and aging. In this study, we asked if the protein repair methyltransferase has a related or additional role in energy metabolism and stress response in the nematode Caenorhabditis elegans. Worms lacking the pcm-1 gene encoding this enzyme exhibit reduced longevity as SDS-isolated dauer larvae and as arrested L1 larvae under starvation stress, while...
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