Article
A new framework for the selection of tag SNPs by multimarker haplotypes.
Journal of biomedical informatics - 1 Dec 2008
Huang Yao-Ting, Chao Kun-Mao
Abstract excerpt
This paper proposes a new framework for the selection of tag SNPs based on haplotypes instead of on a single SNP. The tag SNPs found by this framework form a set of haplotypes completely predictive of the alleles of all untyped SNPs. We refer to this problem as MTMH, which is defined as follows: given a set of SNPs, find a minimum subset of SNPs (called tag SNPs) which defines a set of haplotypes completely...
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