Article
Tag SNP selection in genotype data for maximizing SNP prediction accuracy.
Bioinformatics (Oxford, England) - 1 Jun 2005
Halperin Eran, Kimmel Gad, Shamir Ron
Abstract excerpt
MOTIVATION: The search for genetic regions associated with complex diseases, such as cancer or Alzheimer's disease, is an important challenge that may lead to better diagnosis and treatment. The existence of millions of DNA variations, primarily single nucleotide polymorphisms (SNPs), may allow the fine dissection of such associations. However, studies seeking disease association are limited by the cost of...
Topics
- Algorithms
- Computational Biology
- Computer Simulation
- DNA
- Genomics
- Genotype
- Haplotypes
- Humans
- Polymorphism, Single Nucleotide
- Programming Languages
- Reproducibility of Results