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Article

The complexity of interpreting genomic data in patients with acute myeloid leukemia.

Blood cancer journal - 16 Dec 2016

Nazha A, Zarzour A, Al-Issa K, Radivoyevitch T, Carraway H E, Hirsch C M, Przychodzen B, Patel B J, Clemente M, Sanikommu S R, Kalaycio M, Maciejewski J P, Sekeres M A

Abstract excerpt

Acute myeloid leukemia (AML) is a heterogeneous neoplasm characterized by the accumulation of complex genetic alterations responsible for the initiation and progression of the disease. Translating genomic information into clinical practice remained challenging with conflicting results regarding the impact of certain mutations on disease phenotype and overall survival (OS) especially when clinical variables are...

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Source

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Identifiers

PMID: 27983727
DOI: 10.1038/bcj.2016.115
PMCID: PMC5223150

Genes

ASXL1
CBL
BCOR
FLT3
PRPF8
BCORL1
DHX29
IDH2
JAK2
NPM1
STAG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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