Article
Plasma Cytokine Levels in Relation to Neuropsychiatric Symptoms and Cognitive Dysfunction in Huntington's disease.
Journal of Huntington's disease - 15 Dec 2016
Bouwens Jos A, van Duijn Erik, Cobbaert Christa M, Roos Raymund A C, van der Mast Roos C, Giltay Erik J
Abstract excerpt
BACKGROUND: In Huntington's disease (HD) the innate immune system is activated, as reflected by increased plasma levels of different cytokines. OBJECTIVE: To explore whether increased cytokine levels are associated with neuropsychiatric symptoms and cognitive dysfunction in HD mutation carriers. METHOD: Plasma cytokine levels of TNF-alpha, interleukin (IL)-1ra, IL-1β, IL-5, IL-6, IL-8 and Il-10 were assessed in...
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