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Neuroimmunology of Huntington’s Disease: Revisiting Evidence from Human Studies

1 Jan 2016

Abstract excerpt

Huntington's disease (HD) is a neurodegenerative disorder characterized by selective loss of neurons in the striatum and cortex, which leads to progressive motor dysfunction, cognitive decline, and psychiatric disorders. Although the cause of HD is well described-HD is a genetic disorder caused by a trinucleotide (CAG) repeat expansion in the gene encoding for huntingtin (HTT) on chromosome 4p16.3-the ultimate...

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PMID: 27578922
DOI: 10.1155/2016/8653132

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