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Inflammatory CSF profiles and longitudinal development of cognitive decline in sporadic and GBA-associated PD

2022-10-11

Abstract excerpt

<title>Abstract</title> <p>Inflammation modifies incidence and progression of Parkinson’s disease (PD). By using 30 inflammatory markers in CSF in 498 people with PD and 67 people with Dementia with Lewy Bodies (DLB) we show that: 1) levels of ICAM-1, Interleukin-8, MCP-1, MIP-1 beta, SCF and VEGF were associated with clinical scores and neurodegenerative CSF biomarkers (Aβ1–42, t-Tau, p181-Tau, NFL and α-synucle...

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Identifiers and source

Literature Corpus work
89230017-c18f-5ff1-a32d-4bbba68b2e8c
DOI
10.21203/rs.3.rs-2131597/v1
Open publication

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